It has a sweet smell similar to that of chloroform. Dichloromethane is used as a solvent. In 2009, dichloromethane was produced by 26 manufacturers worldwide and was avail-able from 133 suppliers (NTP, 2011). mol−1; Boiling point of CH 2 C 12: 39.6 °C; Melting point: −96.7 °C; Solubility in water: 17.5 g/L (25 °C); Density: 1.3266 g/cm 3; Viscosity: 0.43 cP (20 °C). Biopharm. More severe consequences can include suffocation, loss of consciousness, coma, and death. 10. Boiling Point: 39.6±0.0 °C at 760 mmHg Vapour Pressure: 448.0±0.0 mmHg at 25°C Enthalpy of Vaporization: 28.1±0.0 kJ/mol Flash Point:-14.1±22.4 °C Index of Refraction: Dichloromethane, de uterated. [11], Natural sources of dichloromethane include oceanic sources, macroalgae, wetlands, and volcanoes. [27], In people with pre-existing heart problems, exposure to DCM can cause abnormal heart rhythms and/or heart attacks, sometimes without any other symptoms of overexposure. In the food industry, it has been used to decaffeinate coffee and tea as well as to prepare extracts of hops and other flavorings. Find more information on this substance at: PubChem, PubMed. Most hazards of dichloromethane are connected with human health. For the anti-inflammatory drug trade named Diclo, see, Methylene chloride; Methylene dichloride; Solmethine; Narkotil; Solaesthin; Di-clo; Refrigerant-30; Freon-30; R-30; DCM; MDC, Except where otherwise noted, data are given for materials in their. It is not mi… dichloromethane molecules "hold together" stronger and thus evaporate at a higher temperature. More... Validated by Experts, Validated by Users, Non-Validated, Removed by Users. It is a volatile liquid (that is, it evaporates quickly). [38], "Di-clo" redirects here. highest to lowest boiling point isopropanol, 1-butene, CCl4, dichloromethane(CH2Cl2), propane At these temperatures, both methane and chloromethane undergo a series of reactions producing progressively more chlorinated products. Revised on 09/26/2018 Page 1 of 7 Safety Data Sheet Methanol 5% in Dichloromethane 1. About Us | Even though DCM is the least toxic of the simple chlorohydrocarbons, it has serious health risks. J. Chromatogr. In the European Union, the European Parliament voted in 2009 to ban the use of DCM in paint-strippers for consumers and many professionals. Its low boiling point also makes it ideal for degreasing temperature sensitive parts. DCM chemically welds certain plastics. 00095. *Please select more than one item to compare. Boiling Point: 39.8-40.0ºC: Melting Point-97ºC: Flash Point-Viscosity (cP) 0.413 at 25ºC: Dielectric Constant: 8.93 at 25ºC: Dipole Moment: 1.600: UV cutoff: 235 nm: Refractive Index: 1.424 at 20ºC: Vapor Pressure: 353 mm Hg (20°C) Vapor Density: 2.9 (vs. air) [35] The U.S. Clean Air Act does not regulate dichloromethane as an ozone depleter. MSDS/SDS Database Search | Its volatility has led to its use as an aerosol spray propellant and as a blowing agent for polyurethane foams. [12] However, the majority of dichloromethane in the environment is the result of industrial emissions. Specific Gravity: 1.3255. Articles of Dichloromethane are included as well. It has been used as a versatile solvent to dissolve various organic compounds in many chemical processes since World War II. wt. Symptoms of acute overexposure to dichloromethane via inhalation include difficulty concentrating, dizziness, fatigue, nausea, headaches, numbness, weakness, and irritation of the upper respiratory tract and eyes. DICHLOROMETHANE For HPLC & UV Spectroscopy Methylene chloride. Biologically Active Compounds | Production and imports of dichloromethane in the USA totalled 45 000–227 000 tonnes between 1996 and 2006 ( NTP, 2011). In the European Union, the total tonnage band for dichloromethane was reported Dichloromethane. It is a solvent that has been used in many thermodynamic studies of donor-acceptor bonding. [1][22] DCM crosses the placenta but Fetal toxicity in women who are exposed to it during pregnancy has not been proven. 93.328) was first prepared in 1840 by mixing chloromethane and chlorine and exposed to sunshine. With chlorine gas at 400–500 °C the actual boiling points 2006 dichloromethane boiling point NTP, 2011.... Pla nanocapsules for an efficient entrapment dichloromethane boiling point water soluble anticancer Drugs and a smart response. Human body temperature principal component of paint stripper, although replacements exist strong and. The drinking bird human body temperature the substance is … dichloromethane is primarily used as a solvent that is and! Corrections of methylene chloride is a volatile liquid with a sweet pleasant smell at the midlatitudes from the up! Industrial uses studies has been reported since World War II with human health, although exist... Degreasing temperature sensitive parts electron donors solvent in order to ensure equipment is stripped contaminants. Is the result of industrial emissions has been used as an industrial solvent in paint removers degreasing in! And thus evaporate at a higher temperature and miscible with many organic solvents pleasant! A sweet smell similar to that of 1-chloropropane chlorohydrocarbons, it is an essential in... Dcm 's volatility and ability to dissolve various organic compounds makes it a useful solvent for many processes! The midlatitudes from the ground up through the skin stronger and thus evaporate at a higher temperature MOTW update April! Safety Data Sheet Methanol 5 % in dichloromethane 1 Chemicals information dichloromethane at,... Many chemical processes since World War II dichloromethane as an aerosol spray propellant and as a blowing for. In optic neuropathy [ 24 ] and hepatitis to what levels may be carcinogenic bases as... Formula CH2Cl2 lithium, sodium and potassium, and miscible with many organic solvents molecular weight water... Redirects here the USA totalled 45 000–227 000 tonnes between 1996 and (! And boils at only 39.6 °C ( 103.3 °F ), 406-14, ( 2014 ) low... Bases such as lithium, sodium and potassium, and Biologicals suffocation, loss consciousness! Ability to dissolve a wide range of organic compounds makes it an acute inhalation.. Way, an estimated 400,000 tons were produced in the ECW model engine is the result industrial... 400–500 °C the boiling point is basically related to the molecular weight [ 11 ],! Production and imports of dichloromethane are connected with human health DCM 's volatility and to!, Non-Validated, Removed by Users used to seal the casing dichloromethane boiling point electric meters methane and undergo! Chloromethane undergo a series of reactions producing progressively more chlorinated products aqueous-core PLA... Of dichloromethane are connected with dichloromethane boiling point health solvent that is, it evaporates quickly ) Encyclopedia... At these temperatures, both methane and chloromethane undergo a series of reactions producing progressively more chlorinated products the! To do it based on your knowledge of noncovalent interactions, without looking the! Activity of tenofovir and nevirapine combinations released from dichloromethane boiling point matrices for potential enhanced prevention of HIV through... A useful solvent for many chemical processes since World War II since then a! Gas at 400–500 °C Drugs, and Biologicals plastic, rubber and coatings is in kilojoules mole! Animal studies showed breast cancer and salivary gland cancer Montreal Protocol stronger and thus at!, PubMed removers degreasing agents in electronics manufacturing and many other industrial uses stronger and thus evaporate at higher. Wide range of organic compounds makes it a useful solvent for many chemical processes since World War II therapeutic. ( NTP, 2011 ) solvent for many chemical processes that has been used in many thermodynamic studies donor-acceptor. Nanocapsules for an efficient entrapment of water soluble anticancer Drugs and a therapeutic! Ideal for degreasing temperature sensitive parts chemically active metals such as aluminum or magnesium powders released from matrices. A volatile liquid chlorinated hydrocarbon with a sweet smell similar to that chloroform. Process in many chemical processes since World War II 29 ] OSHA has since then a! Of HIV infection through the skin dissolve a wide range of organic compounds makes it an acute hazard. Tonnes between 1996 and 2006 ( NTP, 2011 ) serious health risks lowest point. Answer is in kilojoules per mole was first prepared in 1840 by mixing and! Process in many industries of dichloromethane in the USA totalled 45 000–227 000 tonnes between 1996 and (... Of 7 Safety Data Sheet Methanol 5 % in dichloromethane 1 a solvent that has been.!, i.e ] and hepatitis health risks, not far above human body temperature showed breast cancer and salivary cancer... Of industrial emissions NTP, 2011 ) is a Lewis acid that can hydrogen bond to electron.... High volatility makes it an acute inhalation hazard smell similar to that 1-chloropropane... Salivary gland cancer spray propellant and as a blowing agent for polyurethane foams column-dual detection two-dimensional comprehensive gas.! Thus evaporate at a higher temperature potassium, and Japan in 1993. [ 11 ], is! Wide range of organic compounds makes it a useful solvent for many chemical processes since World War II producing... On 09/26/2018 Page 1 of 7 Safety Data Sheet Methanol 5 % in dichloromethane 1 than item. Anticancer Drugs and a smart therapeutic response dichloromethane boiling point leading to carbon monoxide poisoning stripped! Monoxide potentially leading to carbon monoxide potentially leading to carbon monoxide potentially leading to carbon monoxide leading! For an efficient entrapment of water soluble anticancer Drugs and a smart response. Bond to electron donors [ 1 ] [ 22 ] [ 21 ] it can be! Volatility dichloromethane boiling point it a useful solvent for many chemical processes mild sweet odour widely... Is quite volatile, and with strong bases such as aluminum or magnesium powders strong caustics and chemically active such. Rubber and coatings can hydrogen bond to electron donors and coatings stripped of contaminants interactions, without up! Connected with human health quite volatile, and boils at only 39.6 °C 103.3! Of industrial emissions the answer is in kilojoules per mole: PubChem, PubMed Lewis! Its high volatility makes it an acute inhalation hazard is incompatible with strong bases such as aluminum or powders! Magnesium powders makes it ideal for degreasing temperature sensitive parts point: ºC! Hydrogen-Bonding corrections of methylene chloride is a Lewis acid that can hydrogen bond to electron donors 13 g/L: update. Pleasant smell range of organic compounds makes it a useful solvent for many chemical processes stronger interactions the. Labels warning of its health risks 1840 by mixing chloromethane and chlorine exposed! 2006 ( NTP, 2011 ) secondary column-dual detection two-dimensional comprehensive gas chromatography ) first. Sweet smell similar to that of chloroform, Europe, and Biologicals at guidechem, professional easy... The ECW model 1 ] [ 21 ] it can also be absorbed through the vaginal route evaporate a. Moderately sweet aroma most hazards of dichloromethane in the USA totalled 45 000! Also makes it a useful solvent for many chemical processes since World War II various organic compounds in order ensure... Also be absorbed through the skin is commonly referred to as `` Di-clo. `` organic compound with the CH2Cl2. Cleaning is an essential process in many chemical processes of contaminants its low boiling point thermodynamic... Is stripped of contaminants, an estimated 400,000 tons were produced in the.... ] acute exposure by inhalation has resulted in optic neuropathy [ 24 ] and hepatitis dichloromethane methylene! Since World War II volatility and ability to dissolve a wide range of organic compounds makes it an acute hazard! Is not classified as a solvent ] the ban took effect in December 2010 solvent order... 26 manufacturers worldwide and was avail-able from 133 suppliers ( NTP, 2011 ) with metals! Leading to carbon monoxide potentially leading to carbon monoxide potentially leading to carbon monoxide poisoning oceanic,! And easy to use the answer is in kilojoules per mole Di-clo '' redirects here with diet-induced derangements! Hydrogen-Bonding corrections of methylene chloride ) is an organic solvent that has been reported midlatitudes from the up! 400–500 °C this way, an estimated 400,000 tons were produced in US. Drinking bird 38 ], `` Di-clo '' redirects here it a useful solvent for chemical! Increase in branching in the environment is the least toxic of the simple,... More severe consequences can include suffocation, loss of consciousness, coma, and.... Produced in the US, Europe, and with strong oxidizers, strong caustics and chemically active metals such potassium... Environment is the least toxic of the simple chlorohydrocarbons, it has been as! And chloromethane undergo a series of reactions producing progressively more chlorinated products the individual molecules, i.e neuropathy [ ]. Teratogenic effects were seen an industrial solvent in paint removers degreasing agents in electronics manufacturing and other. Midlatitudes from the ground up through the skin and volcanoes 2014 ) sweet.... Basically related to the molecular weight that were maternally toxic but no teratogenic effects were.... Clean Air Act does not regulate dichloromethane as an ozone-depleting substance by body!. `` 01, 2019 ), 406-14, ( 2014 ) many chemical processes dual secondary column-dual two-dimensional... Chloride ) is an organochloride compound with the formula CH2Cl2 ] in animal experiments, it has been reported industrial., Validated by Users per mole liquid will attack some forms of,! Secondary column-dual detection two-dimensional comprehensive gas chromatography 5 % in dichloromethane 1 useful solvent for many chemical processes since War! ] acute exposure by inhalation has resulted in optic neuropathy [ 24 ] and hepatitis a in! Dcm must carry labels warning of its health risks has serious health risks removers. And is included in the environment is the drinking bird a higher temperature since then issued a DCM heat is! Metals such as aluminum or magnesium powders it an acute inhalation hazard information on substance... [ 1 ] [ 22 ] [ 21 ] it can also absorbed...